直肠癌保肛术远端切除多少厘米[1]才能不复发,一直是外科争论的焦点。本研究通过检测癌旁移行黏膜P21、P53蛋白表达,探讨分子切缘的临床意义。1材料与方法1·1材料:收集吉林大学第二医院2002年12月至2004年1月基本外科直肠癌根治术标本34例,其中男性20例,女性14例,年龄(50±12) Rectal cancer anal sphincter resection of how many centimeters [1] in order not to relapse, has been the focus of surgical controversy. In this study, by detecting the expression of P21 and P53 in the adjacent mucosa, the clinical significance of the molecular margin was explored. Materials and Methods 1.1 Materials: 34 cases of radical surgery of rectal cancer were collected from December 2002 to January 2004 in the Second Hospital of Jilin University, including 20 males and 14 females, with an age of (50 ± 12)