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异常血红旦白(Hb)病是一类遗传性的分子病。1910年 Herrick 等首先描述了一例镰刀形细胞贫血。Hahn 等(1921)观察了该种贫血的 Hb 在氧合和脱氧时与红细胞形态变化的规律。1948 Horlein 等报导了第一例 HbM 病,但在当时没有引起广泛注意。一直到 Pauling 发现了 HPS 并阐述了它的电泳特性(1949)以后,Hb 分子病才引起广大科学工作者的重视。以后,各国异常 Hb 的新株不断有所发现。更令人兴奋
Abnormal blood red white (Hb) disease is a class of genetic molecular disease. Herrick et al. First described an example of sickle cell anemia in 1910. Hahn et al (1921) observed the anemia of Hb during oxygenation and deoxygenation and red blood cell morphology changes. 1948 Horlein et al reported the first case of HbM, but at the time did not attract widespread attention. Until Pauling discovered HPS and elucidated its electrophoretic properties (1949), Hb molecular disease has attracted the attention of the majority of scientists. Later, new strains of abnormal Hb in various countries continue to be discovered. Even more exciting