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为进一步降低上海市麻疹疫情,1994～1996年完成了中小学学生(5～19岁)一次麻疹疫苗强化免疫,共计接种1621454人,接种率9819%。流行病学效果评价:强化免疫前后3年平均发病率比较,5～19岁发病率由097/10万下降至015/10万,全市发病率由042/10万下降至016/10万;麻疹血凝抑制(HI)抗体,强化免疫前阴性率8%,几何平均滴度(GMT)1:553,强化免疫后阳性率100%,GMT1:5256,抗体≥4倍增长率944%,效果均极显著。
In order to further reduce the outbreak of measles in Shanghai, a measles vaccine immunization for primary and secondary school students (5-19 years old) was completed between 1994 and 1996 with a total of 162,144 inoculations and a vaccination rate of 9819%. Epidemiological evaluation: the average incidence of 3 years before and after intensive immunization, the incidence of 5 to 19-year-old from 097 / 100,000 down to 015 / 100,000, the city’s incidence dropped from 042 / 100,000 to 016 / 100,000; measles The hemagglutination inhibition (HI) antibody had a negative rate of 8% before immunization, the geometric mean titer (GMT) was 1: 553, the positive rate after immunization was 100%, GMT1: 5256, significant.