论文部分内容阅读
乙型肝炎病毒(HBV)DNA 可与肝细胞癌(HCC)病者的肝细胞核型整合,这支持 HBV 感染是 HCC的病因。本文收集255例原发性 HCC 手术标本,其中222例(86%)其血清乙型肝炎表面抗原(HBsAg)阳性。从中选取瘤组织可作 HBV 抗原组织学检查者204例进行研究,并按肿瘤最大直径是否超过5cm 分为小肿瘤90例和大肿瘤114例。肝脏和肿瘤切片用免疫酶联法检测 HBsag 和乙型肝炎核心抗原(HBcAg),并按 HCC 内淋巴细胞的浸润程度,将宿主肿瘤免疫反应定为无反应、轻反应(局灶性至+)和明显反应((?)～(?))。此外,选用34例血清 HBsAg
Hepatitis B virus (HBV) DNA can be integrated with hepatocytes of patients with hepatocellular carcinoma (HCC), which supports HBV infection as the cause of HCC. This article collected 255 cases of primary HCC surgical specimens, of which 222 cases (86%) of the serum hepatitis B surface antigen (HBsAg) positive. From the selection of tumor tissue for HBV antigen histological examination of 204 cases were studied, and according to the maximum diameter of the tumor is more than 5cm divided into 90 cases of small tumors and 114 cases of large tumors. Liver and tumor sections were tested for HBsAg and hepatitis B core antigen (HBcAg) by enzyme-linked immunosorbent assay. The host immune response was defined as non-responsive and focal (up to +) according to the degree of lymphocyte infiltration in the HCC. And obvious reaction ((?) ~ (?)). In addition, 34 cases of serum HBsAg were selected