在近三十年来,已合成了一系列高灵敏度的杂环偶氮苯酚化合物,并作为分光光度试剂测定了许多金属离子。在这类化合物中,以苯酚环偶氮基的对位上有烷胺基的吡啶偶氮苯酚化合物最为灵敏。但是,大多数这类试剂均微溶于水。 在目前的工作中,我们将磺烷基引到2-(2-吡啶偶氮)-5-氨基苯酚化合物的氨基上。由于引入磺烷基,试剂在水中极易溶解,且比2-(2-吡啶偶氮)-5-氨基苯酚更为灵敏。在所合成的几种试剂中,因为2-(3,5-二溴-2-吡啶偶氮)-5-[N-乙基-N-(3-磺丙基)氨基]苯酚(3, For nearly three decades, a series of highly sensitive heterocyclic azo phenolic compounds have been synthesized and many of the metal ions have been measured as spectrophotometric reagents. Among these compounds, pyridylazo phenols with alkylamino groups on the para position of the azo ring of phenol ring are most sensitive. However, most of these reagents are slightly water-soluble. In our current work, we have introduced sulfoalkyl groups to the amino groups of 2- (2-pyridylazo) -5-aminophenol compounds. Reagents are highly soluble in water due to the introduction of sulfoalkyl groups and are more sensitive than 2- (2-pyridylazo) -5-aminophenol. Among the several reagents that were synthesized, 2- (3,5-dibromo-2-pyridylazo) -5- [N-ethyl-