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作者用划表法评定慢痛病人的针刺临床疗效;用弹簧测痛棒测定痛阈,评定针刺对实验痛的镇痛效果;用放射免疫法测定针刺前后血浆亮氨酸脑啡肽样物质(LEKLS)及血浆皮质醇含量的变化,分析两者的变化与针效的关系。结果表明针刺的临床疗效和对实验痛的镇痛效果均与血浆LEKLS含量变化呈正相关,而与血浆皮质醇含量无关。针刺的临床疗效与痛阈的变化一致。
The author used the table method to assess the clinical efficacy of acupuncture in patients with chronic pain. The pain threshold was measured by spring test and the analgesic effect of acupuncture on experimental pain was evaluated. The levels of leucine enkephalin (LEKLS) and plasma cortisol levels were analyzed, the relationship between the changes and the needle effect was analyzed. The results showed that the clinical efficacy of acupuncture and analgesic effect on experimental pain were positively correlated with plasma LEKLS content, but not with plasma cortisol content. The clinical efficacy of acupuncture and pain threshold changes consistent.