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目的 为了解输血对肾移植患者红细胞免疫功能的影响,探讨红细胞功能检测在肾移植过程中的价值。方法 采用免疫吸附和ELISA 方法,对26例肾移植患者,经移植前和移植后的红细胞免疫功能状态进行了对比研究。结果 肾移植前多次输血可降低肾移植患者的红细胞免疫促进率(23.89±11.46,p<0.01)和提高抑制率(49.56士16.13,p<0.01),使肾移植患者体内的红细胞免疫功能低下。结论 肾移植前少量多次输血可降低排斥反应的发生,延长肾移植的存活率;对供肾体的选择,调整治疗方案及指导免疫抑制剂的应用,对于预测排斥,免疫监视,判断病情,和提高肾移植的存活率均有重要的指导意义。
Objective To understand the influence of blood transfusion on erythrocyte immune function in renal transplant recipients and explore the value of erythrocyte function test in renal transplantation. Methods The immune function of erythrocytes in 26 renal transplant recipients before and after transplantation was compared by ELISA and ELISA. Results Multiple blood transfusions before renal transplantation reduced the rate of erythrocyte immune function in renal transplant recipients (23.89 ± 11.46, p <0.01) and increased the inhibitory rate (49.56 ± 16.13, p <0.01) . CONCLUSIONS: A small number of transfusions before renal transplantation can reduce the incidence of rejection and prolong the survival rate of renal allografts. The selection of donor kidneys, the adjustment of treatment regimens and the guidance of immunosuppressive agents may be helpful in predicting rejection, immune surveillance, And improve the survival rate of renal transplantation have important guiding significance.