本周氏蛋白是Henry Bence—Jones于1844年在一个骨髓瘤病人尿中发现的一种具有特殊凝溶特性的蛋白质。60年代Edelmann等证实这种蛋白质就是免疫球蛋白的轻链二聚体。本周氏蛋白多见于骨髓瘤患者尿中,偶见于淋巴瘤、白血病和癌肿患者。大多数骨髓瘤病人尿中有本周氏蛋白,Hobbs1969年分析了22例骨髓瘤病人,其中IgG旨髓瘤患者65%有尿本周氏蛋白,IgA型70%尿本周氏蛋白阳 This week’s protein is a protein of exceptional peculiarity found by Henry Bence-Jones in 1844 in the urine of a patient with myeloma. The 60’s Edelmann and other confirmed that this protein is the immunoglobulin light chain dimer. This week’s protein more common in patients with myeloma urine, occasionally lymphoma, leukemia and cancer patients. Most myeloma patients have this week’s protein in urine, Hobbs in 1969 analyzed 22 cases of myeloma patients, including IgG leptomycin in patients with 65% of the urine of this week’s protein, IgA type 70% of the urine of Zhou protein positive