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目的 :肾移植术后发生红细胞增多症 (PTE)与内源性促红细胞生成素 (EPO)动态变化的相关性。 方法 :分别测定血透析和肾移植病例 5 5名。将病人按移植前是否接受 EPO治疗 ,分为 EPO治疗组和非治疗组。动态观察手术前后 EPO变化过程。比较治疗组和非治疗组的差异与血象变化。 结果 :两组各观察点 EPO实测值差异无显著性。 EPO治疗组术后可见两次 EPO升高高峰 ,分别为 32 IU / L和 2 1IU / L。贫血的不受 EPO变化的影响 ,呈稳定上升趋势 ,第 2 1天两组血红蛋白平均达到 90 g/ L ,平均术后 8d肾功能达到正常。肾功能延迟恢复病例 ,二次 EPO水平升高过程欠缺。用与未用 EPO组血象变化相同。术后监测 EPO水平 ,有助于预测和判断发生 PTE的相关性。
OBJECTIVE: To investigate the relationship between polycythemia vera (PTE) and dynamic changes of endogenous erythropoietin (EPO) after renal transplantation. Methods: Fifty-five cases of hemodialysis and renal allografts were measured. The patients were treated with EPO before transplantation, divided into EPO treatment group and non-treatment group. Dynamic observation of EPO before and after the change process. The difference between the treatment group and the non-treatment group was compared with that of the blood group. Results: There was no significant difference in EPO between the two groups. EPO treatment group showed two peak EPO rise after surgery, respectively 32 IU / L and 21IU / L. Anemia was not affected by EPO changes, showing a steady upward trend. On the 21st day, hemoglobin of both groups reached an average of 90 g / L, and the average renal function reached normal after 8 days. Delayed recovery of renal function cases, the secondary EPO level increase process is lacking. With the unused EPO blood group changes the same. Postoperative monitoring of EPO levels can be helpful in predicting and judging the incidence of PTE.