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纤维支气管镜(flexible fibroptic bronchos-copy,FFB)用于诊断肺部癌肿时的最佳活检取样次数尚未明确。过去强调应多次取样活检。因为组织过少,取样误差可影响诊断的准确性。但取样次数过多时手术并发症增加。为此,本文对46例(其中26例为中央型可见肿瘤,20例为周围型结节)进行了研究,以确定 FFB 诊断肺部癌肿所需活检的最佳次数。46例最终均确诊为癌肿。46例行活检前均先做肿瘤刷洗。用 Olympus 标准杯状镊取组织,每例患者取6个活检标本,2例只做了4次活栓。每1个活检标本均制成10张连续组织切片。检查第1、4、8、10号切片。结果中央型病变切片114/156(73%)为阳性,
The number of optimal biopsy samplings for flexible fibroptic bronchoscopy (FFB) in the diagnosis of lung cancer has not yet been clarified. In the past, it was emphasized that multiple biopsies should be taken. Because the tissue is too small, sampling errors can affect the accuracy of the diagnosis. However, surgical complications increase when the number of sampling is excessive. For this reason, 46 cases (of which 26 cases were central visible tumors and 20 cases of peripheral type nodules) were studied to determine the optimal number of biopsies required for the diagnosis of lung cancer by FFB. 46 cases were eventually diagnosed with cancer. Tumor brushing was performed on all 46 patients undergoing biopsy. Tissues were taken using Olympus standard cups. Six biopsy specimens were taken from each patient, and only two live thrombi were performed from two patients. Ten consecutive tissue sections were made from each biopsy specimen. Examine slices 1, 4, 8, and 10 Results Central lesions were positive for 114/156 (73%).