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目的:观察头孢他美酯治疗下呼吸道感染的临床疗效和安全性。方法:72例下呼吸道感染患者随机分为2组,各36例。治疗组用头孢他美酯片500 mg,po,bid;对照组用头孢呋辛酯片,500 mg,po,bid,疗程均为5～12 d。结果:治疗组和对照组的临床总有效率分别为86.1%和83.3%,细菌清除率分别为93.3%和90.0%,不良反应发生率均为5.8%。结论:头孢他美酯治疗下呼吸道感染疗效显著,细菌清除能力强,不良反应轻微。
Objective: To observe the clinical efficacy and safety of cefetamet ester in the treatment of lower respiratory tract infection. Methods: 72 cases of lower respiratory tract infection were randomly divided into two groups, 36 cases each. The treatment group with cefetamet 500 mg, po, bid; control group with cefuroxime axetil tablets, 500 mg, po, bid, treatment for 5 ~ 12 d. Results: The total effective rates of the treatment group and the control group were 86.1% and 83.3% respectively, the bacterial clearance rates were 93.3% and 90.0% respectively, and the incidences of adverse reactions were 5.8%. Conclusion: Ceftazidime is effective in treating lower respiratory tract infection with strong bacterial clearance and mild adverse reactions.