经皮射频治疗肝海绵状血管瘤的疗效与安全性分析

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目的评价经皮射频(percutaneous radiofrequency ablation,PRFA)微创治疗肝脏海绵状血管瘤(hepati cavernous hemangiomas,HCHs)的有效性和安全性。方法应用RF-2000射频仪和10电极LeVeen射频针在超声引导下施行PRFA治疗HCHs26例39个病灶直径2.5~11.0cm,其中直径>3.0cm者予分层多点或多次叠合消融。局部麻醉,配合全身镇痛处理。结果26例均成功实施PRFA。反应期2~5天,包括局部疼痛不适、发热、ALT升高等,无胆漏、出血等并发症。23例随访1~5年,平均2年8个月,经一次治疗完全缓解(CR)22例,部分缓解(PR)1例,缓解率(CR+PR)100%;HCHs直径平均缩小68.8%(41.2%~81.5%)。结论在掌握好适应证和操作技巧的前提下,PRFA可发挥微创、安全、有效之优势,可作为治疗HCHs的一种理想选择方法。 Objective To evaluate the efficacy and safety of percutaneous radiofrequency ablation (PRFA) minimally invasive treatment of hepati cavernous hemangiomas (HCHs). Methods 26 cases of HCHs were treated with ultrasound-guided RF-2000 radiofrequency instrument and 10-electrode LeVeen RF needle. Thirty-six lesions of 26 diameter of 2.5 to 11.0 cm in diameter were treated with multifocal or multiple ablation. Local anesthesia, with systemic analgesic treatment. Results 26 cases were successfully implemented PRFA. The reaction period of 2 to 5 days, including local pain discomfort, fever, elevated ALT, no bile leakage, bleeding and other complications. Twenty-three cases were followed up for 1 to 5 years with an average of 2 years and 8 months. Twenty-two cases were treated with complete remission (CR), 1 case partially remission (PR) and 100% remission rate (CR + PR) (41.2% ~ 81.5%). Conclusions PRFA has the advantage of being minimally invasive, safe and effective under the precondition of indications and operation skills, and can be used as an ideal method for the treatment of HCHs.
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