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目的：比较恶性实体瘤患者与正常人血清ＳＩＬ－２Ｒ、ＲＢＣ－Ｃ３ｂＲＲ、ＲＢＣ－ＩＣＲ水平的差异，探讨血清ＳＩＬ－２Ｒ、ＲＢＣ－Ｃ３ｂＲＲ及ＲＢＣ－ＩＣＲ的变化与恶性实体瘤的发生、发展的关系。方法：采用单克隆与多克隆双抗体夹心法及郭峰法分别测定９１例实体瘤患者和４０例正常人血清ＳＩＬ－２Ｒ与ＲＢＣ－Ｃ３ｂＲＲ、ＲＢＣ－ＩＣＲ，并比较它们的差异。结果：恶性实体瘤患者血清ＳＩＬ－２Ｒ增高，ＲＢＣ－ＩＣＲ增多，而ＲＢＣ－Ｃ３ｂＲＲ降低（Ｐ＜０．００１）；不同类型恶性实体瘤病人之间，血清ＳＩＬ－２Ｒ、ＲＢＣ－Ｃ３ｂＲＲ及ＲＢＣ－ＩＣＲ相比无显著差异性（Ｐ＞０．０５）；血清ＳＩＬ－２Ｒ水平与ＲＢＣ－Ｃ３ｂＲＲ显负相关（ｒ＝－０．５１，Ｐ＜０．０５），与ＲＢＣ－ＩＣＲ显正相关（ｒ＝０．４８，Ｐ＜０．０５）。结论：恶性实体瘤患者血清ＳＩＬ－２Ｒ升高，红细胞免疫功能低下，其两者的变化可能与恶性肿瘤的发生、发展有密切关系
Objective: To compare the serum levels of SIL-2R, RBC-C3bRR, and RBC-ICR in patients with malignant solid tumors and normal subjects, and to investigate the changes of serum SIL-2R, RBC-C3bRR, RBC-ICR, and the occurrence and development of malignant solid tumors. relationship. METHODS: Serum SIL-2R, RBC-C3bRR, and RBC-ICR were measured in 91 patients with solid tumors and 40 normal controls using monoclonal and polyclonal sandwiches and Guo Feng. The differences were compared. Results: Serum SIL-2R increased, RBC-ICR increased, and RBC-C3bRR decreased in patients with malignant solid tumors (P<0.001); serum SIL-2R, RBC-C3bRR, and RBC-C among different types of malignant solid tumors There was no significant difference in ICR (P>0.05); serum SIL-2R level was negatively correlated with RBC-C3bRR (r=-0.51, P<0.05) and positively correlated with RBC-ICR ( r=0.48, P<0.05). Conclusion: The serum level of SIL-2R in patients with malignant solid tumors is elevated and the immune function of red blood cells is low. The changes of both may be closely related to the occurrence and development of malignant tumors.