论文部分内容阅读
目的 :了解急性白血病T细胞亚群的改变及免疫规律 ,指导临床使用免疫调节剂以及其它的药物治疗 ;方法 :采用间接免疫荧光法 ,测定 2 6例急性白血病患儿外周血T淋巴细胞亚群 ;结果 :T淋巴细胞白血病的全T细胞 (CD3)、辅助性T细胞 (CD4)、抑制性T细胞 (CD8)和CD4/CD8(分别为 1 2 .0 1± 6 .0 8、4.0 0± 0 .0 7、6 .5 9± 1 .6 3、1 .1 0± 0 .0 7)显著降低 ,提示了小儿急性白血病发病与机体免疫反应状态有关 ;结论 :T淋巴细胞亚群的水平可做判断急性白血病治疗后完全缓解指标之一来推广应用。
OBJECTIVE: To investigate the changes of T lymphocyte subsets and immunologic rules in acute leukemia and to guide the clinical use of immunomodulators and other drug therapy. Methods: T lymphocyte subsets in 26 children with acute leukemia were detected by indirect immunofluorescence ; Results: The levels of total T cells (CD3), helper T cells (CD4), suppressor T cells (CD8) and CD4 / CD8 of T lymphoblastic leukemia were 120.01 ± 6.08.0 ± 0 .0 7,6 .5 9 ± 1 .6 3,1 .1 0 ± 0 .0 7) was significantly reduced, suggesting that the incidence of childhood acute leukemia and the immune response status; Conclusion: T lymphocyte subsets To determine the level of acute leukemia can be one of the indicators of complete remission to promote the application.