本文应用染色体原位杂交方法对c-mye基因在人类染色体上的位置进行定位研究。结果表明,在100个正常人染色体分裂相中,38％的杂交银粒位于8号染色体上,其中80％在8q24位置。在其它染色体上,杂交银粒随机分布。c-myc基因的激活在许多人类肿瘤的形成和发展中起重要作用。研究其在正常及恶变细胞中位置的变化,为探讨癌变机理,诊断肿瘤,防止癌的形成提供依据。 In this paper, the location of c-mye gene in human chromosomes was mapped using chromosome in situ hybridization. The results showed that in 100 normal human chromosome split phase, 38% of hybrid silver particles located on chromosome 8, of which 80% at 8q24 position. On other chromosomes, hybrid silver particles are randomly distributed. Activation of c-myc gene plays an important role in the formation and development of many human tumors. To study the changes of its location in normal and malignant cells, in order to explore the mechanism of carcinogenesis, diagnosis of cancer, to provide a basis for preventing the formation of cancer.