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肾上腺髓质肽是一种较强的舒血管物质。在急性心肌梗塞病人（特别是并发充血性心力衰竭）血浆肾上腺髓质肽增高。其增高与体液潴留、交感神经兴奋性增强，和／或肺血管床压力增高相关。肾上腺髓质肽对急性心肌梗塞致缩血管物质过量起一个对抗作用。
Adrenomedullin is a strong vasodilator. In patients with acute myocardial infarction (especially congestive heart failure) plasma adrenomedullary peptide increased. Its increase is associated with fluid retention, increased sympathetic excitability, and / or increased pressure on the pulmonary vascular bed. Adrenomedullin plays an antagonistic role in the excessive synthesis of vasoconstrictors in acute myocardial infarction.