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目的 研究产前用地塞米松治疗对早产儿呼吸窘迫综合征 (RDS)发生率的影响。 方法 对 16 4例早产儿按产前地塞米松治疗组及非治疗组进行回顾性分析。 结果 产前使用地塞米松治疗可使早产儿 RDS发生率显著降低 ,主要表现在极低出生体重儿中 ;产前地塞米松治疗对其它肺部疾病发生率的降低无显著意义。 结论 产前地塞米松治疗可促进胎肺的成熟并改善其换气功能 ,对极低出生体重儿尤为重要 ,并在促进胎肺成熟方面具有高选择性
Objective To study the effect of prenatal dexamethasone treatment on the incidence of respiratory distress syndrome (RDS) in preterm infants. Methods A total of 164 preterm infants underwent prenatal dexamethasone treatment and non-treatment group. Results Prenatal dexamethasone treatment significantly reduced the incidence of RDS in preterm infants, which was mainly found in very low birth weight infants. Prenatal dexamethasone treatment had no significant effect on the incidence of other pulmonary diseases. Conclusion Prenatal dexamethasone treatment can promote fetal lung maturation and improve its ventilation function, especially for very low birth weight children, and in the promotion of fetal lung maturation with high selectivity