某些α_1受体拮抗剂,对组胺H_1受体、5-羟色胺受体、多巴胺受体或α_2受体也有影响,故不良作用彼此不同。吲哚哌胺、酮舍林、乌拉地尔等的中枢神经系统副作用较多,酮舍林尚有抗血小板聚集作用。特拉唑嗪、多沙唑嗪、三甲唑嗪等较之吲哚哌胺、乌拉地尔、酮舍林等更类似于哌唑嗪。特拉唑嗪、多沙唑嗪半减期长,轻中度高血压患者每日只需服药1次,可安全地并用利尿剂及/或β阻滞剂。 Some alpha 1 receptor antagonists also have effects on histamine H 1 receptors, serotonin receptors, dopamine receptors or α 2 receptors, so their adverse effects are different from each other. Indolepeptamine, ketamine, urapidil and other side effects of the central nervous system more ketone ketamine has anti-platelet aggregation. Terazosin, doxazosin, tazozine, and the like are more similar to prazosin than indolpenem, urapidil, ketastrin and the like. Terazosin, doxazosin Long-term, mild to moderate hypertensive patients need only take a daily dose of 1, safely with diuretics and / or beta blockers.