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诺氟沙星为人工合成的喹诺酮类抗菌药物。在药品微生物限度检查中,由于其抗菌作用强,用常规方法能检出制剂中被污染的霉菌数,但要检出被污染的细菌数则非常困难。本实验比较了三种方法检测诺氟沙星胶囊的细菌数。
Norfloxacin is a synthetic quinolone antibacterial drug. Because of its strong antibacterial activity, the number of molds contaminated in the formulation can be detected by conventional methods in the limit test of pharmaceutical microorganisms. However, it is very difficult to detect the number of contaminated bacteria. The experiment compared the three methods to detect norfloxacin capsules.