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目的探讨欣普贝生用于妊娠晚期促宫颈成熟的有效性和安全性。方法按对照研究的方法,将60例妊娠晚期、无阴道分娩禁忌、单胎头位的孕妇随机分为阴道放置欣普贝生的研究组和小剂量催产素静滴的对照组,比较2组用药前及用药6,12,h后的B ishop评分。结果研究组给药12h Bishop评分,27例提高>2分,而对照组仅14例提高>2分,2组比较有显著性差异(P<0.01)。结论欣普贝生是一种安全有效的促宫颈成熟的药物。
Objective To explore the efficacy and safety of Enbubeixin in promoting cervical ripening in late pregnancy. Methods According to the control study, 60 pregnant women with contraindications of vaginal delivery and contraindications of vaginal delivery were randomly divided into study group in which vaginal placement of Hinbutsone and control group of low-dose oxytocin intravenous infusion were given. Before treatment and medication 6,12, h after B ishop score. Results In the study group, the Bishop score of 12h was improved, while in the control group, the score of Bishop was increased> 2 points compared with 14 cases in the control group (> 2 points). There was significant difference between the two groups (P <0.01). Conclusion Thipepsin is a safe and effective cervical ripening drug.