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高脂血症是动脉粥样硬化〈AS〉的主要危险因素之一。近年来由于递度超速离心术、肝素-琼脂糖亲和色谱法细胞培养等先进技术的发展和应用,增加了对各种脂蛋白的认识,使我们有可能从分子生物学和宏观观察两种水平来讨论几种主要脂蛋白和AS的关系。这里只就血浆脂蛋白运转系统和β-极低密度脂蛋白(B-VLDL)、低密度脂蛋白(LDL)和高密度脂蛋白(HDL)与AS的关系略加讨论。一、血浆脂蛋白运转系统血浆脂蛋白运转系统的研究近年来有了一定的进展,已经大致弄清了乳糜微粒
Hyperlipidemia is one of the major risk factors for atherosclerosis . In recent years, due to the development and application of advanced ultracentrifugation, heparin - agarose affinity chromatography cell culture and other advanced technologies, increased understanding of various lipoproteins, so that we may from the molecular biology and macroscopic observation of two Level to discuss the relationship between several major lipoproteins and AS. Only a brief discussion of the relationship between plasma lipoprotein functioning system and B-VLDL, LDL, and HDL with AS is discussed here. First, the plasma lipoprotein system The study of plasma lipoprotein system has been made some progress in recent years, has been largely clear chylomicron