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目的探讨牙周非手术治疗对慢性牙周炎患者血脂及血清C反应蛋白(CRP)的影响。方法选择身体健康的慢性牙周炎患者36例,随机分为牙周非手术治疗组和对照组,每组各18例。分别在治疗前、治疗后3个月检测两组患者的血脂和血清CRP水平,并进行统计学分析。结果治疗3个月后,治疗组血清CRP水平由治疗前(2.3±0.7)mg/dl降至(1.8±0.6)mg/dl,差异有统计学意义(P<0.05),平均降低0.498 mg/dl(95%CI=0.265~0.731 mg/dl),此降低值与PLI、PD≥7 mm位点百分比的改善程度呈正相关关系(r=0.746、0.621,P<0.01)。治疗前后血脂水平差异无统计学意义(P>0.05)。结论积极有效的治疗慢性牙周炎可降低患者血清CRP水平。
Objective To investigate the effects of periodontal nonoperative treatment on serum lipids and serum C-reactive protein (CRP) in patients with chronic periodontitis. Methods 36 healthy periodontitis patients were randomly divided into periodontal non-surgical treatment group and control group, with 18 cases in each group. Blood lipids and serum CRP levels were measured before treatment and 3 months after treatment in both groups, and statistical analysis was performed. Results After 3 months of treatment, the serum CRP level in the treatment group decreased from (2.3 ± 0.7) mg / dl to (1.8 ± 0.6) mg / dl before treatment, with a significant difference (P <0.05) dl (95% CI = 0.265-0.731 mg / dl). The decrease was positively correlated with the percent improvement of PLI and PD≥7 mm (r = 0.746,0.621, P <0.01). There was no significant difference in blood lipid levels before and after treatment (P> 0.05). Conclusion Active and effective treatment of chronic periodontitis can reduce serum CRP levels in patients.