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相同年龄段(6~7岁)学龄前儿童280名,男、女各半,分为锌组(Zn组)、锌加复合微量营养素组(ZnM组)和单纯补充微量营养素组(M组),每组80人,另外40名儿童为对照组,采用双盲法进行营养干预实验,实验周期为10周。结果显示,重庆市城区学龄前儿童近80%处于边缘性锌缺乏状态,一半以上儿童血铅超过0.483μmol/L的安全标准,经过10周营养干预后,发现每日补充16mg锌的同时再添加多种复合微量营养素能有效增加儿童血锌含量、降低血铅水平,同时明显增强儿童的认知功能,而单纯补锌效果并不理想。本研究儿童认知功能的改善可能与体内良好的锌营养状况、铅负荷减少有关。
There were 280 preschoolers in the same age group (6-7 years old), divided into two groups: zinc group (Zn group), zinc plus micronutrient group (ZnM group) and micronutrient supplement group (M group) , 80 in each group, another 40 children as the control group, the double-blind method for nutritional intervention experiments, the experimental period of 10 weeks. The results showed that nearly 80% of pre-school children in Chongqing were marginal zinc deficient, more than half of the children with blood lead over 0.483μmol / L safety standards, after 10 weeks of nutritional intervention, found that daily supplementation of 16mg zinc at the same time Adding a variety of complex micronutrients can effectively increase children’s blood zinc levels, reduce blood lead levels, while significantly enhancing children’s cognitive function, while the effect of zinc alone is not ideal. The improvement of cognitive function in children in this study may be related to the good nutrition status of zinc and lead load in vivo.