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目的:了解西宁地区婴幼儿分离的耐甲氧西林金黄色葡萄球菌(MRSA)临床分布特点及其耐药性,为儿科临床合理选用抗菌药物提供参考。方法:分析本院2008年1月—2011年1月住院婴幼儿分离的社区获得性MRSA(CA-MRSA)资料。结果:329株CA-MRSA分离自此期间住院婴幼儿的血液、脓汁、痰液等。所有菌株均对万古霉素、利奈唑胺敏感。结论:婴幼儿社区获得性金黄色葡萄球菌感染中,CA-MRSA的分离率占63.5%,故儿科临床医生加强对CA-MRSA的监测,重视抗生素的合理使用。
Objective: To understand the clinical distribution and drug resistance of methicillin-resistant Staphylococcus aureus (MRSA) isolated from infants and young children in Xining area and to provide a reference for rational selection of antibiotics in pediatrics. Methods: The data of community-acquired MRSA (CA-MRSA) isolated from hospitalized infants in our hospital from January 2008 to January 2011 were analyzed. Results: 329 strains of CA-MRSA were isolated from blood, pus, sputum and so on hospitalized infants during this period. All strains were sensitive to vancomycin and linezolid. Conclusion: The prevalence of CA-MRSA in infants and young children receiving community-acquired Staphylococcus aureus is 63.5%. Therefore, pediatric clinicians should strengthen the monitoring of CA-MRSA and pay attention to the rational use of antibiotics.