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目的:探讨西宁地区急性白血病患者的牙龈表现,为临床白血病的早期诊断提供依据。方法:总结、分析近4年来就诊于我院血液科的68例急性白血病患者的牙龈表现。结果:39例以牙龈出血为主要表现,占57.4%;16例以牙龈增生、肥大为主,占23.5%;8例发生牙龈溃疡、坏死,占11.8%;5例出现继发感染,占7.4%。结论:由于西宁地处高海拔地区,牙龈组织中的多种因子如白细胞介素8、碱性磷酸酶等活性受到抑制,其白血病患者的牙龈临床表现与文献报道的又有所不同。正确全面地认识白血病的口腔表征,有助于口腔医师对白血病作出早期诊断。
Objective: To explore the gingival manifestations of patients with acute leukemia in Xining area and provide the basis for the early diagnosis of clinical leukemia. Methods: To summarize and analyze the gingival manifestations of 68 cases of acute leukemia patients treated in our department of hematology in recent 4 years. Results: Gingival bleeding was the main manifestation in 39 cases, accounting for 57.4%. Gingival hyperplasia and hypertrophy in 16 cases accounted for 23.5%. Gingival ulcer and necrosis occurred in 8 cases (11.8%). Secondary infection occurred in 5 cases (7.4% %. Conclusion: Due to the high altitude in Xining, gingival tissues such as interleukin-8, alkaline phosphatase and other activities were inhibited. The clinical manifestations of gingival in patients with leukemia were different from those reported in the literature. Correct and comprehensive understanding of oral signs of leukemia, help dentists early diagnosis of leukemia.