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目的探讨替硝唑联合盐酸左氧氟沙星治疗慢性盆腔炎的临床疗效。方法收集106例慢性盆腔炎患者作为研究对象,根据患者的治疗方式将其分为联合用药组(53例)与单独用药组(53例)。单独用药组患者仅采用替硝唑治疗,联合用药组采用替硝唑联合盐酸左氧氟沙星治疗,观察患者的治疗效果和不良反应。结果联合用药组患者总有效率为96.23%,优于单独用药组(P<0.05);联合用药组患者的不良反应发生率为18.87%,略高于单独用药组,但组间比较差异无统计学意义(P>0.05)。结论替硝唑联合盐酸左氧氟沙星治疗慢性盆腔炎具有良好的临床疗效,且不会提高不良反应发生率,是一种安全有效的治疗方案。
Objective To investigate the clinical effect of tinidazole combined with levofloxacin hydrochloride in the treatment of chronic pelvic inflammatory disease. Methods A total of 106 patients with chronic pelvic inflammatory disease were enrolled in this study. Patients were divided into two groups according to their treatment: combination therapy (53 cases) and treatment alone (53 cases). Tinidazole alone was used in the treatment group. Tinidazole combined with levofloxacin hydrochloride was used in the combination group to observe the therapeutic effect and adverse reactions of the patients. Results The total effective rate was 96.23% in the combination group, which was better than that in the single drug group (P <0.05). The incidence of adverse reactions in the combination group was 18.87%, slightly higher than that in the single drug group, but there was no statistical difference between the two groups Significance (P> 0.05). Conclusion Tinidazole combined with levofloxacin hydrochloride in the treatment of chronic pelvic inflammatory disease has a good clinical efficacy, and does not increase the incidence of adverse reactions, is a safe and effective treatment.