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目的对康复新液保留灌肠联合柳氮磺吡啶治疗溃疡性结肠炎的疗效进行系统性分析。方法对建库至今的康复新液保留灌肠联合柳氮磺吡啶治疗和单独运用柳氮磺吡啶治疗患者的疗效的随机对照试验行荟萃分析,计算OR值,评估试验质量和异质性,。结果最终纳入4项研究。经Meta分析其合并OR值为3.40(95%CI:1.55-7.45),统计检验Z=3.05,P<0.01。结论当前研究显示,康复新液联合柳氮磺吡啶治疗溃疡性结肠炎的疗效明显优于单独使用柳氮磺吡啶。
Objective To systematically analyze the curative effect of Kangfu Xinye retention enema combined with sulfasalazine in the treatment of ulcerative colitis. Methods A meta-analysis of randomized controlled trials of Rehmannia New fluid retention enema combined with sulfasalazine and the treatment of patients receiving sulfasalazine alone was performed. The OR was calculated and the quality and heterogeneity of the trial were evaluated. The results eventually included 4 studies. The Meta-analysis of the combined OR was 3.40 (95% CI: 1.55-7.45), statistical test Z = 3.05, P <0.01. Conclusions The current study shows that Kangfuxin Solution combined with sulfasalazine is superior to sulfasalazine alone in the treatment of ulcerative colitis.