50年代初即有人报告长期应用肾上腺皮质激素病人术后发生不可逆休克死亡,尸解发现肾上腺皮质萎缩。之后,此种肾上腺皮质功能不全逐渐受到重视,文献上建议对这些病人在应激时应补充皮质类固醇,并为大多数临床医师所接受,因而发生术后休克情况的报道渐少,但对长期激素治疗病人围手术期应用皮质类固醇的指征、剂量和方法尚未规范化,以致仍偶有急性肾上腺危象发生。 In the early 1950s, it was reported that long-term use of adrenal cortical hormone patients after irreversible shock death occurred, autopsy found adrenal cortical atrophy. Later, this type of adrenocortical insufficiency was gradually taken into account. The literature suggests that these patients should be supplemented with corticosteroids during stress and accepted by most clinicians. As a result, fewer reports of postoperative shock occur, but for the long term. The indications, doses, and methods of perioperative corticosteroid use in hormone therapy patients have not been standardized so that occasional acute adrenal crisis occurs.