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报告1例乳头状汗管囊腺癌。患者女,52岁。左侧头皮及额部疣状丘疹、肿块50余年,增大、破溃10年。皮肤科检查:额部左侧及头皮可见疣状增生斑块,其上无毛发,局部增生明显处出现破溃,有脓性分泌物渗出,压之有轻微疼痛。皮损组织病理检查:乳头状病变向囊腔突起,典型的有两层或多层结构的囊腔上皮,外层是胞质嗜酸性的高柱状上皮细胞,内层是有卵圆形核深染的小的肌上皮细胞,有明显的核异形性和异常核分裂象。免疫组化示癌胚抗原(CEA)及核增殖抗原(Ki-67)(约20%)均阳性。结合临床、组织病理及免疫组化结果诊断为乳头状汗管囊腺癌。
One case of papillary cystadenocarcinoma was reported. Female patient, 52 years old. Left scalp and forehead verrucous papules, lumps more than 50 years, increased, ruptured 10 years. Dermatology examination: the Ministry of the left and the scalp visible verrucous hyperplasia plaque, no hair on it, local hyperplasia obvious ulceration, there purulent discharge exudation, the pressure of a slight pain. Skin lesions histopathological examination: papillary lesions protruding to the cysts, the typical two or more layers of cystic epithelium, the outer cytoplasm of eosinophilic high columnar epithelial cells, the inner layer is oval nucleus deep Dyed small myoepithelial cells, there is a clear nuclear allomorphosis and abnormal mitotic figures. Immunohistochemistry showed CEA and Ki-67 (about 20%) were positive. Combined with clinical, histopathological and immunohistochemical findings of papillary cystadenocarcinoma.