溶出度是指药物从片剂或胶囊剂等固体制剂在规定溶剂中涛出的速度和程度。抗生素药品的溶出度多采用分光光度法测定。具体有吸收系数法如利福平片[1]，对照品对照法如头抱氨节胶囊[1]，自身对照法如乙酸螺旋霉素片[见卫生部标准：（95）卫药材字（02）号）。实际工作中用于对照 Dissolution refers to the speed and extent to which pharmaceuticals come out of a given solvent from a solid formulation such as a tablet or capsule. Antibiotic drug dissolution more determined by spectrophotometry. Specific absorption coefficient method such as rifampicin tablets [1], the control method of reference substance such as the head of ammonia capsule [1], self-control method such as acetic acid spiramycin tablets [see Ministry of Health standards: (95) 02)). Actual work for comparison