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系统性硬化症(Systemic Sclerosis,SSc)是一种以小动脉或微血管及广泛结缔组织硬化为特点的自身免疫性疾病。本病主要累及20～50岁的成年人,而儿童罕见。近期曾诊治1例年仅14岁的幼年系统性硬化症患者,现报道如下。患者,女性,14岁,主因双手遇冷变色11个月于2011年9月16日就诊。患者从2010年11月开始遇冷后双手远端指间关节以远皮肤变白和麻木感,得暖后变紫、潮红,数分钟后恢复正常肤色,麻木感消失。此后皮肤变色的范围逐渐扩大,已
Systemic Sclerosis (SSc) is an autoimmune disease characterized by arteriolar or microvascular and extensive connective tissue sclerosis. The disease mainly affects 20 to 50-year-old adults, while children are rare. Recently diagnosed and treated a case of only 14 years old juvenile systemic sclerosis patients are reported below. Patient, female, 14 years old, mainly due to hands discoloration 11 months in September 16, 2011 treatment. Patients from November 2010 began after the hands of both hands distal interphalangeal joint skin whitening and numbness, get warm after the purple, flushing, a few minutes to restore normal skin tone, numbness disappeared. Since then the range of skin discoloration gradually expanded, already