Larvicidal and repellent activity of medicinal plant extracts from Eastern Ghats of South India agai

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Objective:To evaluate the larvicidal and repellent activities of ethyl acetate and methanol extracts ofAcacia concinna (A. concinna),Cassia siamea(C. siamea),Coriandrum sativum (C. sativum),Cuminum cyminum(C. cyminum),Lantana camara (L. camara),Nelumbo nucifera (N. nucifera)Phyllanthus amarus (P. amarus),Piper nigrum (P. nigrum) andTrachyspermum ammi(T. ammi) againstAnopheles stephensi(An. stephensi) andCulex quinquefasciatus (Cx. quinquefasciatus).Methods:The larvicidal activity of medicinal plant extracts were tested against early fourth-instar larvae of malaria and filariasis vectors. The mortality was observed 24 h and48 h after treatment, data were subjected to probit analysis to determine the lethal concentrations (LC50 andLC90) to kill50 and 90per cent of the treated larvae of the tested species. The repellent efficacy was determined against two mosquito species at five concentrations (31.25, 62.50, 125.00, 250.00, and 500.00 ppm) under the laboratory conditions.Results: All plant extracts showed moderate effects after24h and 48h of exposure; however, the highest activity was observed after24h in the leaf methanol extract ofN. nucifera, seed ethyl acetate and methanol extract ofP. nigrumagainst the larvae of An. stephensi(LC50 =34.76, 24.54 and30.20 ppm) and againstCx. quinquefasciatus (LC50= 37.49, 43.94 and57.39ppm), respectively. The toxic effect of leaf methanol extract ofC. siamea, seed methanol extract ofC. cyminum, leaf ethyl acetate extract ofN. nucifera, leaf ethyl acetate and methanol extract ofP. amarusand seed methanol extract ofT. ammiwere showed100% mortality againstAn. stephensi andCx. quinquefasciatus after48 h exposer. The maximum repellent activity was observed at500 ppm in methanol extracts ofN. nucifera, ethyl acetate and methanol extract ofP. nigrum and methanol extract ofT. ammi and the mean complete protection time ranged from30 to150 min with the different extracts tested. Conclusions:These results suggest that the leaf and seed extracts ofC. siamea, N. nucifera, P. amarus,P. nigrum andT. ammi have the potential to be used as an ideal ecofriendly approach for the control of the An. stephensi andCx. quinquefasciatus.
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