论文部分内容阅读
目的了解不明原因发热患者最终诊断为人布鲁氏菌病的临床特征。方法回顾性分析2012年2月—2014年4月以不明原因发热诊断入院,最终诊断为人布鲁氏菌病的患者临床资料。结果 8例病例纳入研究,8例患者均为男性,都有疫区、牛羊等接触史。临床表现主要为发热(8/8)、关节疼痛及乏力(3/8),睾丸肿痛(2/8)。实验室检查提示试管凝集试验(SAT)阳性为8/8,虎红平板凝集试验(RBPT)阳性为8/8,血培养均阴性。8例患者入院均未诊断明确,经利福喷丁0.15/d联合多西环素0.2/d,口服21 d后间隔3~5 d再次口服21 d,8例患者均治愈,无复发。结论布鲁氏菌病临床表现的多样化及隐匿性需引起临床医师重视。
Objective To understand the clinical characteristics of patients with unexplained fever in the diagnosis of human brucellosis. Methods The clinical data of patients diagnosed as human brucellosis by retrospective analysis from February 2012 to April 2014 were retrospectively analyzed. Results Eight cases were included in the study. All eight patients were male. All had epidemic areas, history of exposure to cattle and sheep. Clinical manifestations mainly fever (8/8), joint pain and fatigue (3/8), testicular swelling and pain (2/8). Laboratory tests showed a positive test tube agglutination test (SAT) of 8/8, tiger red plate agglutination test (RBPT) positive 8/8, blood cultures were negative. All 8 patients were admitted to hospital without diagnosis. Rifampicin 0.15 / d and doxycycline 0.2 / d were given orally for 21 days and then orally for 21 days. All 8 patients were cured without relapse. Conclusion The diversity and occultness of clinical manifestations of brucellosis should be paid more attention by clinicians.