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目的:建立起吸收系数法对吡嗪酰胺片药物的具体溶出度测定方式。方法:利用紫外分光光度法中所存在的吸收系数法来对吡嗪酰胺片进行检测。结果:本方法和实际对照品之间的检测结果并没有较为明显的差距。结论:吸收系数法对吡嗪酰胺片的检测极为快捷、精确、方便,可以利用该检测方式来作为对药品药效的控制方式。
Objective: To establish a method for determining the specific dissolution of pyrazinamide tablets by the absorption coefficient method. Methods: Pyrazinamide tablets were detected by absorption coefficient method in UV spectrophotometry. Results: The test results between this method and the actual control did not show a significant difference. Conclusion: The absorption coefficient method for the detection of pyrazinamide tablets is very fast, accurate and convenient, and can be used as a control method for drug efficacy.