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目的 :评价肝动脉化疗栓塞与 B超引导下注射细胞因子 (白介素 - II) (PEI)联合治疗中晚期肝癌的疗效。方法 :6 0例经证实为巨块型肝癌随机分为两组 ,在进行 TAE的间歇期 ,30例在 B超引导下瘤体内注射细胞因子 (IL- 2 )。结果 :对照组 (单纯 TAE) 1年生存率为 33% ,综合组 (TAE+ B超引导下瘤体内药物注射 ) 1年生存率为 5 6 .7%。 AFP下降幅度单纯组为 6 0 % ,综合组为 76 .6 %。结论 :TAE与 B超引导下瘤体内注射细胞因子联合治疗中晚期肝癌 ,可提高中晚期肝癌治疗疗效
Objective: To evaluate the efficacy of transcatheter arterial chemoembolization combined with B-guided injection of cytokines (interleukin-II) (PEI) in the treatment of advanced liver cancer. Methods: Totally 60 patients with massive liver cancer were randomly divided into two groups. During the intermission of TAE, 30 patients underwent B-ultrasound for the injection of cytokines (IL-2). Results: The 1-year survival rate of the control group (simple TAE) was 33%. The 1-year survival rate of the combined group (TAE + B ultrasound guided intratumor injection) was 56.7%. The decrease of AFP was 60% in the simple group and 76.6% in the combined group. Conclusion: TAE and B-guided tumor cytotoxicity combined with advanced hepatocellular carcinoma can improve the treatment of advanced liver cancer