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参考Yam am oto 的N-乙酰-α-D-氨基半乳糖苷酶(NAGal)检测方法, 检测了肿瘤病人在手术前后血清NAGal的水平,并与正常人对照。结果发现术前增高, 与正常人比较:P< 0.005 有显著性差异; 手术后: 0.05< P< 0.1, 酶水平呈下降趋势。而诊断肾小管损伤的N-乙酰氨基葡萄糖苷酶(NAGlu) 水平无显著差异( P> 0.5)。因此NAGal是肿瘤病人放疗、化疗、手术治疗效果以及预后判断的一个指标。
NAM-alfa-D-aminogalactosidase (NAGal) assay method of Yam am oto was used to measure the serum NAGal levels in tumor patients before and after surgery and compared with normal controls. The results showed that preoperative increase, compared with normal: P <0.005 was significantly different; after surgery: 0.05
0.5). Therefore, NAGal is an indicator of radiotherapy, chemotherapy, surgical treatment and prognosis of cancer patients.