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目的 研究吉非罗齐降甘油三酯的作用及意义。方法 对 36例脂质代谢异常病人 ,早、晚餐前服吉非罗齐 6 0 0mg/次 ,2次 /d ,分别于第 4、8周采血化验。结果 服药 4周、8周末TG分别降低 5 4.8%和 5 9.2 % ,总有效率达 10 0 % ;TC分别降低 2 1.4%和 2 3.6 % ,总有效率达 81.6 % ;皆P <0 .0 1。对HDL有增高作用 ,P <0 .0 5 ,对TC/HDL也有显著降低作用 (P <0 0 1)用于动脉粥样硬化 (AS)和冠心病 (CHD)的一级预防
Objective To study the effect and significance of gemfibrozil hypothalamic triglycerides. Methods Thirty - six patients with abnormal lipid metabolism were treated with gemfibrozil at 600 mg / time and 2 times / d before breakfast and dinner. Blood samples were collected at 4 and 8 weeks respectively. Results After 4 and 8 weeks of treatment, TG decreased by 5 4.8% and 52.2%, respectively, with a total effective rate of 10 0%. TC decreased by 21.4% and 23.6%, respectively, with a total effective rate of 81.6%; all P 0 .0 1. (P <0. 05), also had a significant reduction in TC / HDL (P <0.01) for the primary prevention of atherosclerosis (AS) and coronary heart disease (CHD)