选取我院门诊60例早期糖尿病肾病患者,随机分为对照组,治疗1组和治疗2组分别给予缬沙坦80mg和160mg,疗程为8周。结果缬沙坦80mg和160mg组除较对照组可降低血压、糖化血红蛋白外,还可显著降低尿微量白蛋白,并且160mg组优于80mg组。结论缬沙坦可降低尿蛋白保护早期糖尿病肾病,延缓糖尿病肾病的进展。 Sixty patients with early diabetic nephropathy in our hospital were randomly divided into control group, treatment group 1 and treatment group 2 were given valsartan 80mg and 160mg, the course of treatment was 8 weeks. Results Compared with the control group, the valsartan 80 mg and 160 mg groups were able to lower the blood pressure and glycosylated hemoglobin, but also significantly lower urinary albumin, and the 160 mg group was superior to the 80 mg group. Conclusion Valsartan can reduce urinary protein protection of early diabetic nephropathy, delay the progress of diabetic nephropathy.