桥本脑病(Hashimotos encephalopathy,HE)目前倾向于称为自身免疫性甲状腺疾病相关性糖皮质激素敏感性脑病。临床上是一种以甲状腺自身抗体增高为特征,以急性或亚急性起病,临床表现为癫痫/卒中样发作和精神异常等多种临床症状的神经系统功能紊乱为主的自身免疫性脑病。1966年由Brain等首次报道。本病少见,既往主要见于国外文献报道病例。近10年来国内报道病例 Hashimotos encephalopathy (HE) currently tends to be referred to as autoimmune thyroid disease-associated glucocorticoid-sensitive encephalopathy. Clinically, it is an autoimmune encephalopathy characterized by increased thyroid autoantibodies, acute or subacute onset, clinical manifestations of epilepsy / stroke-like episodes and psychiatric disorders and other clinical symptoms of nervous system disorders. First reported by Brain et al in 1966. The rare disease, previous mainly seen in foreign literature reported cases. Nearly 10 years reported cases in China