人工合成血纤蛋白粘附肽（１２肽）ｃＤＮＡ，与低分子量单链尿激酶基因重组，获得血纤蛋白粘附肽与低分子量单链尿激酶的融合基因。将此融合基因重组入ｐＢＶ２２０表达载体并在大肠杆菌中表达，表达产物具有与天然尿激酶相同的抗原性和溶纤活性，同时兼具血纤蛋白粘附肽（１２肽）的抗血纤蛋白单体聚合的活性 Artificial synthesis of fibrin adhesion peptide (12 peptide) cDNA, and low molecular weight single chain urokinase gene recombination, to obtain the fusion protein of fibrin adhesion peptide and low molecular weight single chain urokinase. The fusion gene was recombined into pBV220 expression vector and expressed in E. coli. The expressed product had the same antigenicity and fibrinolytic activity as native urokinase, and at the same time, anti-fibrin Monomer polymerization activity