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通过查阅国内外相关文献,对不同体积比例的水/乙醇润湿剂以及不同的用量对制得的软材性质和微丸的物理性质的影响及其在挤出滚圆过程中的作用进行整理归纳和总结。润湿剂水/乙醇在挤出滚圆法制备微丸中具有显著的影响,调整润湿剂水/乙醇的比例和用量对微丸的制备有重要的意义。
By referring to the relevant literatures at home and abroad, the influence of the volume ratio of water / ethanol wetting agent and different dosage on the properties of the prepared soft material and the physical properties of the pellets and their role in the extrusion spheronization process are summarized And concluded. Wetting agent water / ethanol in the extrusion spheronization preparation of pellets have a significant impact, adjust the wetting agent water / ethanol ratio and the amount of the preparation of pellets of great significance.