目的 研究唐古特大黄的化学成分.方法 采用多种色谱技术进行分离纯化,应用质谱、核磁等技术确定化合物的结构.结果 从唐古特大黄的根和根茎中分离得到β-谷甾醇、大黄酚、芦荟大黄素、大黄素甲醚、大黄酸、大黄素等20个化合物.结论 4’-羟基苯基-2-丁酮(9)、4’-羟基苯基-2-丁酮-4’-O-β-D-(2“-O-桂皮酰基-6”-O-没食子酰基)-葡萄糖苷(12) 和4’-羟基苯基-2-丁酮-4’-O-β-D-(2“-O-没食子酰基-6”-O-(4“’-羟基)-桂皮酰基)-葡萄糖苷(13)为首次从该种植物中分离得到.”,“Aim To study the chemical constituents of the root and rhizome of Rheum tanguticum Maxim. ex Balf. Methods Chemical constituents were isolated and purified by many chromatographic methods, and their structures were elucidated by MS, NMR, and others. Results Twenty compounds were isolated and their structures were identified as β-sitosterol, chrysophanol, aloe-emodin, physcion, rhein, emodin, etc. Conclusion Among these compounds, 4-(4’-hydroxyphenyl)-2-butanone, 4-(4’-hydroxyphenyl)-2-butanone-4’-O-β-D-(2”-O-cinnamoyl-6“-O-galloyl)-glucopyranoside and 4-(4’-hydroxyphenyl)-2-butanone-4’-O-β-D-(2”-O-galloyl-6"-O-p-coumaroyl)-glucopyranoside were isolated from the root and rhizome of Rheum tanguticum for the first time.