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目的探讨三维适形放疗联合紫杉醇+顺铂(TP)治疗晚期非小细胞肺癌患者的临床疗效。方法选取2012年1月至2014年1月收治的晚期非小细胞肺癌患者78例作为研究对象,按随机数字表法将其分为对照组与观察组,各39例。对照组患者给予TP方案化疗,观察组患者在对照组基础上给予三维适形放疗。比较两组患者的临床疗效。结果经治疗后,观察组患者总有效率为66.7%,明显高于对照组的43.6%,差异有统计学意义(P<0.05);两组患者的不良反应发生率差异无统计学意义(P>0.05)。结论三维适形放疗联合TP治疗晚期非小细胞肺癌患者临床疗效明显,可以提高患者生命质量。
Objective To investigate the clinical efficacy of three-dimensional conformal radiotherapy combined with paclitaxel + cisplatin (TP) in the treatment of advanced non-small cell lung cancer. Methods Seventy-eight patients with advanced non-small cell lung cancer who were admitted from January 2012 to January 2014 were selected as the research object. According to the random number table, they were divided into control group and observation group, with 39 cases in each group. Patients in the control group received TP regimen and patients in the observation group received three-dimensional conformal radiotherapy on the basis of the control group. The clinical efficacy of the two groups was compared. Results After treatment, the total effective rate in the observation group was 66.7%, which was significantly higher than that in the control group (43.6%) (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P > 0.05). Conclusion Three-dimensional conformal radiotherapy and TP are effective in treating patients with advanced non-small cell lung cancer and can improve the quality of life of patients.