皮肌炎是一种横纹肌慢性、非化脓性炎症伴特异性皮肤改变的免疫性疾病,肾上腺皮质激素对其有较好疗效。临床上对病情重或难治性患者单用肾上腺皮质激素很难奏效,常加用免疫抑制剂,如甲氨蝶呤、环磷酰胺、硫唑嘌呤等进行治疗,但部分病人疗效仍不满意。来氟米特(leflunomide)是19 Dermatomyositis is a chronic, non-purulent inflammation of the striated muscle with a change in the specific immune skin disease, adrenal hormones have a good effect on it. Clinically severe or refractory patients with adrenocorticotropic hormone alone is difficult to work, often with immunosuppressive agents, such as methotrexate, cyclophosphamide, azathioprine, etc. for treatment, but some patients are still not satisfied with the efficacy . Leflunomide is 19