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[目的]观察丹栀逍遥丸联合西药治疗多囊卵巢综合征(PCOS)疗效。[方法]使用随机平行对照方法,将78例住院患者按病志号抽签方法简单随机分为两组。对照组39例二甲双胍、环丙孕酮、来曲唑口服;复方醋酸环丙孕酮,月经周期第5d开始,1片/d,共21d为1个周期,连服3个月经周期;二甲双胍缓释片,每日晚餐前30min服用,0.5g/次,连续30d;来曲唑2.5mg,1次/d,月经来潮第3d开始,共5d。治疗组39例,丹栀逍遥丸,3g/次,2次/d,西药治疗同对照组。1个治疗周期(3个月经周期)为1疗程。观测临床症状、LH、T、血清胰岛素、优势卵泡、排卵、不良反应。[结果]1hINS、2hINS、T、LH、FINS均明显降低(P<0.05),治疗组优于对照组(P<0.05)。排卵率治疗组86.57%显著高于对照组65.04%(P<0.05);妊娠率治疗组66.67%高于对照组43.59%(P<0.05)。[结论]丹栀逍遥丸联合西医治疗多囊卵巢综合征,疗效满意,提高排卵率及妊娠率,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Danzhi Xiaoyao Pill combined with western medicine on polycystic ovary syndrome (PCOS). [Methods] Using randomized parallel control method, 78 inpatients were randomly divided into two groups randomly according to the method of lot drawing of the disease. Control group, 39 cases of metformin, cyproterone, letrozole oral; compound cyproterone acetate, menstrual cycle began 5d, 1 / d, a total of 21d for a cycle, and even served three menstrual cycles; Metformin Release tablets, daily 30min before dinner taking, 0.5g / time, continuous 30d; letrozole 2.5mg, 1 / d, the first three days of menstrual cramps, a total of 5d. Treatment group 39 cases, Dan Zhi Xiaoyao Pill, 3g / times, 2 times / d, Western medicine treatment with the control group. 1 treatment cycle (3 menstrual cycle) for a course of treatment. Observation of clinical symptoms, LH, T, serum insulin, dominant follicles, ovulation, adverse reactions. [Results] The levels of 1 h INS, 2 h INS, T, LH and FINS were significantly decreased (P <0.05), and the treatment group was better than the control group (P <0.05). The ovulation rate in treatment group was 86.57%, which was significantly higher than that in control group (65.04%, P <0.05). Pregnancy rate in treatment group was 66.67% higher than that in control group (43.59%, P <0.05). [Conclusion] Danzhi Xiaoyao Pills combined with Western medicine in the treatment of polycystic ovary syndrome, with satisfactory results, improve ovulation rate and pregnancy rate, no serious adverse reactions, it is worth promoting.