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对31例老年人轻、中度高血压患者,首次舌下含服5mg心痛定,在给药后10′、20′、30′、40′、60′、120′记录血压和心率。结果表明,给药后各次平均收缩压、平均舒张压,均明显低于给药前(P值<0.001),给药前后平均心率无明显差异(P值均>0.05),给药后无明显副作用发生。提出:舌下含服心痛定5mg可作为老年人轻、中度高血压患者的起始剂量。
In 31 elderly mild to moderate hypertensive patients, the first sublingual 5mg of nifedipine was given subcutaneously, and the blood pressure and heart rate were recorded at 10 ’, 20’, 30 ’, 40’, 60 ’and 120’ after administration. The results showed that the average systolic blood pressure and mean diastolic blood pressure after administration were significantly lower than those before administration (P <0.001), and there was no significant difference in average heart rate before and after administration (P> 0.05) Obvious side effects occur. Proposed: sublingual convulsions given 5mg can be used as the elderly mild to moderate hypertensive patients starting dose.