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测定了101例异位妊娠(EP)、49例正常宫内孕(NIUP)、24例先兆流产(TA)及32例难免流产(IA)妇女血清孕酮(P)和β-hCG水平及26例EP妇女间隔48~72小时的血清β-hCG水平。结果:血清P水平均值在EP与NIUP或TA组间有非常显著差异(P<0.001),在EP与IA组间及未破裂型EP(UREP)与破裂型EP(REP)组间的差异无显著性(P>0.05)。以血清P49.2nmol/L为临界值筛选EP与NIUP、TA、IA,其敏感性为93.1%,特异性分别为75.5%、83.3%、21.2%。血清β-hCG水平均值在UREP与REP组间亦有非常显著差异(P<0.001)。26例EP患者间隔48~72h血清β-hCG水平上升率均<60.0%。指出血清P测定对EP与NIUP及TA筛选的价值大,并认为血清β-hCG接近8000IU/L的EP患者,应视为有破裂高危的病例。
The serum levels of progesterone (P) and β-hCG in 101 cases of ectopic pregnancy (EP), 49 cases of normal intrauterine pregnancy (NIUP), 24 cases of threatened abortion (TA) and 32 cases of inevitable abortion Example EP Serum β-hCG levels in women 48 to 72 hours apart. Results: There was a significant difference (P <0.001) between the mean serum P level and the NIUP or TA group, between the EP group and the IA group, and between the unruptured EP (UREP) and the ruptured EP (REP) There was no significant difference (P> 0.05). The serum P49.2nmol / L as the cutoff value of screening EP and NIUP, TA, IA, the sensitivity was 93.1%, the specificity was 75.5%, 83.3%, 21.2%. Serum β-hCG levels were also significantly different between the UREP and REP groups (P <0.001). The serum β-hCG levels in 26 patients with EP at 48-72h were all higher than 60.0%. Pointed out that serum P determination of EP and NIUP and TA screening of large value, and that serum β-hCG close to 8000IU / L of EP patients should be considered as a high risk of rupture cases.