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经前综合征(PMS)包括许多身心变化,始于经前7～14d,而月经一开始就几乎自行缓解。最常见的综合证是应激性、腹胀、乳房不适、抑郁、焦虑、手指和踝关节肿胀以及疲乏。 PMS的许多特证与注射一定剂量催乳激素后观察到的效应相似。PMS患者也许对正常浓度的催乳激素较敏感,或其血清中的催乳激素浓度有时稍微升高。以前一次研究表明,从饮食中必需脂肪酸衍生的前列腺素E_1,(PGE_1)削弱催乳激素的生物活性。在催乳激素中缺乏PGE_1则增强其作用,从而
Premenstrual syndrome (PMS) includes many physical and psychological changes, beginning in the first 7 ~ 14d, and menstruation almost self-remission from the beginning. The most common syndromes are stress, bloating, breast discomfort, depression, anxiety, swelling of the fingers and ankle, and fatigue. Many of the specifics of PMS are similar to those observed after injecting a dose of prolactin. PMS patients may be more sensitive to normal concentrations of prolactin, or the serum prolactin concentration sometimes slightly increased. Previous studies have shown that the prostaglandin E 1 (PGE 1) derived from dietary essential fatty acids impairs the bioactivity of prolactin. The lack of PGE 1 in prolactin enhances its action, thus