胸腺对脊椎动物免疫系统的发生,特别是T淋巴细胞的成熟起着关键性作用.已知无免疫活性的前T细胞在胸腺内发育成熟为有免疫活性的T细胞,近来还了解到T细胞对自身MHC抗原的识别能力是在胸腺内获得的,在病理上T细胞淋巴瘤发生于胸腺.这三点都说明T细胞的成熟需要与胸腺的基质细胞相互接触.有关这方面的研究资料还很少.曾有报导在组织培养中见到淋巴细胞能主动进入其他细胞中,也有人报导在患 The thymus plays a key role in the development of vertebrate immune system, especially T lymphocyte maturation.It is known that pre-immune T cells are matured into immunocompetent T cells in the thymus and T cell Recognition of own MHC antigens is obtained in the thymus, and pathologically T-cell lymphoma occurs in the thymus, indicating that the maturation of T cells requires mutual contact with the thymus stromal cells. Few have been reported in tissue culture to see lymphocytes can actively enter other cells, it was also reported in the affected