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阻塞性睡眠呼吸暂停低通气综合征(OSAS)是一种病因不明的睡眠呼吸疾病,临床表现有夜间睡眠打鼾伴呼吸暂停和白天嗜睡,其直接发病机制为上气道的狭窄和阻塞.安氏Ⅱ类错牙合畸形中存在上气道口咽段结构性狭窄,OSAS 患者尤其是非肥胖型患者都有较明显的Ⅱ类矢状骨面型高角的颅颌面特征.口腔矫治器的应用能够在治疗错牙合畸形的同时改善气道狭窄,被认为是OSAS的一种有效治疗方法.该文将陈述阻塞性睡眠呼吸暂停综合征目前常用的治疗方法,为伴安氏Ⅱ类错牙合畸形的治疗提供指导性意见.“,”Obstructive sleep apnea syndrome(OSAS),a conventional sleep-related breathing disorder,is characterized by repetitive upper airway obstructions and disruptive night snoring during sleep,accompanied by excessive daytime sleepiness,neurocognitive dysfunction,cardiovascular disorders,metabolic dysfunction,and impaired mood and quality of life,usually along with malocclusion.Oropharyngeal airway structural segment stenosis exists in Angle Class Ⅱ malocclusion.OSAS patients,especially obese patients,apparently have craniofacial characteristics of high angle of Class Ⅱ sagittal facial type.Improving malocclusion and modifying pharyngeal patency by oral appliance therapy have been suggested as an alternative to various treatment modalities for OSAS.These modalities applied in treating malocclusion and OSAS can be effective.Thus,in this review,several methods in treatment and therapeutic efficacy of OSAS will be represented,in addition,the morphological changes of pharyngeal airway passage and relieving symptoms of OSAS will also be illustrated in order to offer some constructive suggestions to the future treatment of OSAS with malocclusion.